ABSTRACT
ABSTRACT Objective: This study aimed to evaluate the factors affecting recurrence in subacute granulomatous thyroiditis (SAT). Materials and methods: A total of 137 patients with SAT were enrolled in the study; 98 (71.5%) were women and 39 (28.5%) were men. The patients received either steroid or nonsteroidal anti-inflammatory drug (NSAID) for eight weeks. Erythrocyte sedimentation rate (ESR), C-reactive protein, serum thyroid-stimulating hormone (TSH), free triiodothyronine, free thyroxine (FT4), anti-thyroid peroxidase antibodies and thyroglobulin antibodies, neutrophil, lymphocyte, platelet, neutrophil to lymphocyte ratio, and platelet to lymphocyte ratio levels were evaluated. In addition, recurrence rates were compared between patients who received NSAID treatment and those who received steroid therapy. Results: Treatment modality and pretreatment TSH, FT4, and ESR were significantly different between patients with and without recurrence (p = 0.011, 0.001, 0.004, and 0.026, respectively). Compared with patients without recurrence, those with recurrence had higher pretreatment TSH levels, but lower FT4 and ESR levels. On logistic regression analysis, treatment modality was found to be an independent risk factor for recurrence. The risk of recurrence was higher in those taking steroids than in those taking NSAIDs (p = 0.015). The optimal TSH cutoff value for recurrence was 0.045 μIU/mL, with a sensitivity of 83.3% and specificity of 76% (AUC 0.794, 95% CI 0.639-0.949). Conclusions: The risk of SAT recurrence was higher with steroid therapy than with NSAIDs. Patients who had mild thyrotoxicosis had relatively high recurrence rate and may need a relatively longer duration of treatment.
ABSTRACT
Aims: The combination of an eating disorder and diabetes mellitus (DM) puts patients at high risk of mortality and morbidity. The purpose of this study was to determine the association of eating attitudes between metabolic control and quality of life in patients with type 1 DM (T1DM) and type 2 DM (T2DM) and with regard to different type of medical treatments. Study Design: A descriptive cross-sectional study. Place and Duration of the Study: Ege University Hospital Endocrine Polyclinic, December, 2013 – April, 2014.İzmir, Turkey. Methodology: One hundred and fifty adults with T1DM (n=52) and T2DM (n=98) were evaluated using general information questionnaire, Eating Attitude Test (EAT-40 Turkish version), SF-36 quality of life questionnaire. Biochemical data were collected from the hospital records retrospectively. Data were analyzed with SPSS version 15.0 programme. Results: The prevalence of disorders of eating attitudes in patients was found to be 39.3%. Metabolic control and quality of life were not related with eating attitudes in patients with DM. No significant correlation was found between the types of DM in terms of eating attitudes and medical treatments. Conclusion: DM is considered to be a risk factor for the development of eating disorders. In this area further studies are needed to develop diabetes specific eating behavior rating scales.